KEGG   Homo sapiens (human): 84254
Entry
84254             CDS       T01001                                 
Symbol
CAMKK1, CAMKKA
Name
(RefSeq) calcium/calmodulin dependent protein kinase kinase 1
  KO
K00908  calcium/calmodulin-dependent protein kinase kinase 1 [EC:2.7.11.17]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05034  Alcoholism
Network
nt06528  Calcium signaling
  Element
N01648  Ca2+/CAM-CAMK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09165 Substance dependence
   05034 Alcoholism
    84254 (CAMKK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    84254 (CAMKK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.17  Ca2+/calmodulin-dependent protein kinase
     84254 (CAMKK1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  CAMKK family
   84254 (CAMKK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal ABC1
Other DBs
NCBI-GeneID: 84254
NCBI-ProteinID: NP_115670
OMIM: 611411
HGNC: 1469
Ensembl: ENSG00000004660
UniProt: Q8N5S9
Structure
Position
17:complement(3860315..3893053)
AA seq 505 aa
MEGGPAVCCQDPRAELVERVAAIDVTHLEEADGGPEPTRNGVDPPPRARAASVIPGSTSR
LLPARPSLSARKLSLQERPAGSYLEAQAGPYATGPASHISPRAWRRPTIESHHVAISDAE
DCVQLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQ
AAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVME
VPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF
EGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILA
LHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSE
EEHCSVVEVTEEEVKNSVRLIPSWTTVILVKSMLRKRSFGNPFEPQARREERSMSAPGNL
LVKEGFGEGGKSPELPGVQEDEAAS
NT seq 1518 nt   +upstreamnt  +downstreamnt
atggaggggggtccagctgtctgctgccaggatcctcgggcagagctggtagaacgggtg
gcagccatcgatgtgactcacttggaggaggcagatggtggcccagagcctactagaaac
ggtgtggaccccccaccacgggccagagctgcctctgtgatccctggcagtacttcaaga
ctgctcccagcccggcctagcctctcagccaggaagctttccctacaggagcggccagca
ggaagctatctggaggcgcaggctgggccttatgccacggggcctgccagccacatctcc
ccccgggcctggcggaggcccaccatcgagtcccaccacgtggccatctcagatgcagag
gactgcgtgcagctgaaccagtacaagctgcagagtgagattggcaagggtgcctacggt
gtggtgaggctggcctacaacgaaagtgaagacagacactatgcaatgaaagtcctttcc
aaaaagaagttactgaagcagtatggctttccacgtcgccctcccccgagagggtcccag
gctgcccagggaggaccagccaagcagctgctgcccctggagcgggtgtaccaggagatt
gccatcctgaagaagctggaccacgtgaatgtggtcaaactgatcgaggtcctggatgac
ccagctgaggacaacctctatttggtgtttgacctcctgagaaaggggcccgtcatggaa
gtgccctgtgacaagcccttctcggaggagcaagctcgcctctacctgcgggacgtcatc
ctgggcctcgagtacttgcactgccagaagatcgtccacagggacatcaagccatccaac
ctgctcctgggggatgatgggcacgtgaagatcgccgactttggcgtcagcaaccagttt
gaggggaacgacgctcagctgtccagcacggcgggaaccccagcattcatggcccccgag
gccatttctgattccggccagagcttcagtgggaaggccttggatgtatgggccactggc
gtcacgttgtactgctttgtctatgggaagtgcccattcatcgacgatttcatcctggcc
ctccacaggaagatcaagaatgagcccgtggtgtttcctgaggagccagaaatcagcgag
gagctcaaggacctgatcctgaagatgttagacaagaatcccgagacgagaattggggtg
ccagacatcaagttgcacccttgggtgaccaagaacggggaggagccccttccttcggag
gaggagcactgcagcgtggtggaggtgacagaggaggaggttaagaactcagtcaggctc
atccccagctggaccacggtgatcctggtgaagtccatgctgaggaagcgttcctttggg
aacccgtttgagccccaagcacggagggaagagcgatccatgtctgctccaggaaaccta
ctggtgaaagaagggtttggtgaagggggcaagagcccagagctccccggcgtccaggaa
gacgaggctgcatcctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (19)   
   RefSeq(nuc) (3)   
   GenBank (8)   
   EMBL (8)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (52)   

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